Using a pharmacokinetic model that accounts for both absorption and elimination, the tool generates a dynamic graph showing how your caffeine levels peak and decline over 24 hours. This helps you understand the impact of your caffeine intake on alertness, sleep, and potential side effects.
You can input multiple caffeine doses, specifying the amount and time of consumption. The tool also allows you to adjust key pharmacokinetic parameters, such as the time to peak concentration (Tmax) and caffeine’s half-life, for a personalized simulation.
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Much of the logic for this tool comes from: White JR Jr, Padowski JM, Zhong Y, Chen G, Luo S, Lazarus P, Layton ME, McPherson S. Pharmacokinetic analysis and comparison of caffeine administered rapidly or slowly in coffee chilled or hot versus chilled energy drink in healthy young adults. Clin Toxicol (Phila). 2016;54(4):308-12. doi: 10.3109/15563650.2016.1146740. PMID: 27100333; PMCID: PMC4898153. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898153
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